GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.06 | 2.78E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.15 | 1.61E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | EML5 | chr14:89081205-89259157:- | 0.29 | 6.67 | 7.13E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.08 | 5.03E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.99 | 4.23E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.16 | 1.56E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | NKX6-1 | chr4:85414436-85419387:- | 0.51 | 8.83 | 1.94E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7847663 | chr9:100544868 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.19 | 1.32E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7850258 | chr9:100549013 | BMPR1A | chr10:88516396-88684944:+ | 0.25 | 6.28 | 7.76E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7850258 | chr9:100549013 | EML5 | chr14:89081205-89259157:- | -0.31 | -7.09 | 4.74E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7850258 | chr9:100549013 | EPDR1 | chr7:37960163-37991539:+ | -0.32 | -7.08 | 5.18E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7850258 | chr9:100549013 | GGT5 | chr22:24615623-24641110:- | -0.26 | -6 | 3.98E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7850258 | chr9:100549013 | NKX6-1 | chr4:85414436-85419387:- | -0.5 | -8.49 | 2.62E-16 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7864322 | chr9:100548934 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.19 | 1.33E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7864322 | chr9:100548934 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.07 | 2.56E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |